IMG_4835Despite purification respectively polishing processes in protein preparation, it’s not possible to create proteins without host cell proteins. In addition to these process-related impurities there are also product-related impurities to be caused by protein modifications. 

Protein impurities may generate undesired side effects.

So characterizing protein impurities is a key requirement of ICH Q6B.

We identify and quantify all the proteins in your mixture using mass spectrometry. By carrying out a bioassay, we can also see if the impurities are influencing the efficacy. Finally, we eliminate the unwanted proteins one step at a time by focusing on the differences in their characteristics.

The process is tailored to your needs because every client’s requirements are different.

 We can search for: 

 

Your contact for Protein Impurities at Protagen Protein Services GmbH

Thomas Flad

Dr Thomas Flad

Director Business Development
Our business development team will be happy to assist you with your project.

Phone: +49 (0) 231 9742-6100
Email: salesproteinservices@ProtagenProteinServices.com